Hi,
Seems like Network and AD DNS configuration issue with Exchange setup, what sort of Network connectivity and bandwidth is available? Did you tried to review the suggested setup and configuration for Multi site setup over here - https://video2.skills-academy.com/en-us/exchange/high-availability/plan-ha?view=exchserver-2019#:%7E:text=Each%20DAG%20must%20have%20no,can%20be%20added%2C%20as%20needed
Also the Client connectivity process check the link https://video2.skills-academy.com/en-us/exchange/clients/clients?view=exchserver-2019
Hope this helps.
JS
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