Hello there,
Do you have any complex GPO in your domain?
Does all apps loads slowly or only specific apps?
Log on to each affected computer by using an account that has administrative credentials, and then delete the following hidden file and folder if they exist:
File: C:\Users\Default\AppData\Local\Microsoft\Windows\WebCacheLock.dat
Folder: C:\Users\Default\AppData\Local\Microsoft\Windows\WebCache
Hope this resolves your Query !!
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