There are a number of "file not found" errors in your log.
It looks like your server is missing some components and/or there is a mismatch between the installed Dot Net framework, and the application requirements.
Is your IIS worker process set to use the correct .Net CLR version?
You would need to ask your developer or the support team for the software that you running as to how you can verify that the server has the correct components installed.
Message: Could not load file or assembly 'System.Design' or one of its dependencies. The system cannot find the file specified.
Message: Could not load file or assembly 'System.Windows.Forms' or one of its dependencies. The system cannot find the file specified.
Message: Could not load file or assembly 'Wisej.Core.Design' or one of its dependencies. The system cannot find the file specified.
Message: Could not load file or assembly 'Wisej.Web.Design' or one of its dependencies. The system cannot find the file specified.