For your first question -This setting does not directly affect Microsoft Edge or Google Chrome. Edge and Chrome have their own security settings and policies, separate from Internet Explorer. Changes made to Internet Explorer's settings won't automatically apply to Edge.
For your second question -If a website is registered as a trusted site, it may override Group Policy-configured security settings, such as the "Allow websites to prompt for information using scripted windows" option. However, this behavior can vary depending on your environment's specific configuration and the policies in place.