Yes, it is possible to use a YubiKey for Windows 10 login, including as an administrator. The YubiKey 5 Series, which includes the YubiKey 5 NFC you mentioned, supports this feature. https://support.yubico.com/hc/en-us/articles/360013708460-Yubico-Login-for-Windows-Configuration-Guide.
Please ensure you understand these limitations and consult the Yubico Login for Windows Configuration Guide for detailed instructions. https://support.yubico.com/hc/en-us/articles/360013708460-Yubico-Login-for-Windows-Configuration-Guide
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