Hi,
Please note only topics listed on the homepage of Q&A forum will be supported. Thus, for your question of Biztalk, we are sorry and have limited knowledge to assist.
Per searching, here is the article covers some known issues about BizTalk Server as well as some forums might be related.
BizTalk Server: List of Errors and Warnings, Causes, and Solutions
https://social.technet.microsoft.com/wiki/contents/articles/7204.biztalk-server-list-of-errors-and-warnings-causes-and-solutions.aspx#BizTalk_Runtime_Issues
Forums:
https://techcommunity.microsoft.com/t5/biztalk-server/ct-p/BizTalkServer
https://social.msdn.microsoft.com/Forums/en-US/home?category=biztalkserver
Hope this helps and please help to accept as Answer if the response is useful.
Thanks,
Jenny