Hi,
Thanks for posting in Microsoft MECM Q&A forum.
Technically speaking, yes, it's possible and there is no issue to install sccm agent on the read only domain controllers. However, for security consideration, it's recommended that you either manage domain controllers with a very restricted access SCCM environment, or not at all.
Similar thread for your reference:
ConfigMgr Client on Domain Controllers
Thanks for your time.
Best regards,
Simon
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