Hi @Ma Alkam,
If you locate to C:\Program Files\Microsoft Office\root\Office16
, then double click "Winword.exe", "Excel.exe" and other Office applications, will them opened properly?
Please check if this article is helpful to you: https://www.winhelponline.com/blog/windows-cant-find-winword-excel-exe-cant-open-avast-avg/. It explains Avast Cleanup, AVG TuneUp, CCleaner Professional, or any other tweaking program on the computer may cause such issue.
(Please Note: Since the web site is not hosted by Microsoft, the link may changed without notice. Microsoft does not guarantee the accuracy of this information.)
If the answer is helpful, please click "Accept Answer" and kindly upvote it. If you have extra questions about this answer, please click "Comment".
Note: Please follow the steps in our documentation to enable e-mail notifications if you want to receive the related email notification for this thread.